Posted by Admin
Post Date : Thursday July 19 2007

JF is a 64-year old woman diagnosed with right breast ductal carcinoma in situ on Jan 6, 2006. She was HER2 neu negative and estrogen positive. Prior to her scheduled lumpectomy she started using the Efudex (5-fluorouracil) topically twice daily for 14 days. Within 4 days of using Efudex the blood vessel that was visible and the one that could be felt were gone. The first application of the Efudex was to the main visible blood vessel going to the tumor. It disappeared within 2 days of using Efudex. She then pushed down in the area until she could feel the spiculated portion of the tumor (the huge cluster of blood vessels that where next to the tumor. She rubbed this area between her finger with the Efudex and the vessels in the speculated area were gone in 2 days. The breast turned black and blue during the Efudex this time. The nipple also turned bright red. Over the 14 days all the discoloration subsided. Shortly after finishing the Efudex treatment she stopped Arthrotec. She had been taking it for 10 years. She took this drug for arthritis that was caused by multiple injuries including a broken back in 1984; 3 herniated discs; and a knee replacement in both knees 2003. Two new blood vessels formed within one day of stopping the Arthrotec. JF immediately reinstated the Arthrotec at ½ dose. The blood vessels quickly disappeared again. She had a lumpectomy performed on January 26, 2006 to remove the tumor. The ultrasound prior to the surgery revealed a purse like structure that grew at and under the nipple where the tumor was removed. She had a mole removed at age 15 near the nipple where the cancer was first found. When the tumor was analyzed after lumpectomy 20% of the tumor was “dead”. Blood vessels were also not visible and there were no malignant cells found beyond the margin of the tumor. However the sentinel node was positive for microinvasion. Her surgeon was shocked that the Efudex had effectively killed 20% of the tumor, the blood vessels and may have resulted in the clean margins. Prior to this diagnosis, she had basal cell carcinoma on her nose in 2001 and it was treated with Efudex and Mohs surgery. Her primary physician had told her to use Efudex anytime she saw suspicious skin lesions which is what prompted her to use it on her breast. The oncologist recommended radiation therapy plus chemotherapy. By the end of July 2006 JF completed 33 radiation treatments with 7 electron boost treatments to the right breast. JF refused chemotherapy. She also started taking 8 teaspoons per day of Poly-MVA in June 2006. In November 2006 she felt pain in her right breast and saw a red patch of tissue at the core of the nipple. Her breast surgeon said it was still clear, but she was very concerned. She increased Poly-MVA to 20 teaspoons per day for one week and all of these breast symptoms disappeared. After one week, she resumed the Poly-MVA at 8 teaspoons per day.

Prior to the diagnosis of breast cancer, JF was diagnosed with a 5 mm lesion in the left kidney in December 1996. She had 4 episodes of shingles in 1996 as well. Her oncologist decided to watch the suspicious lesion in the kidney and no treatment was recommended. However, after the lumpectomy was performed and before radiation treatment began, JF received a CT scan and MRI that included the abdomen and kidney area. The lesion in the kidney had grown to 2 cm mass. JF did her research and found that cryoablation was the safest and least invasive way to treat the tumor. She had cryoablation performed at Columbia Presbyterian Hospital in NYC on August 4, 2006. Her medical history also includes fibromyalgia diagnoses in 1998, Sjogren’s syndrome in 1989 and Hashimoto’s disease in 1989. All of these have responded to treatment.

On January 8, 2007 JF had a mammography. Only microcalcification was seen, there was no evidence of cancer. However, in February the breast pain and redness around the core of the nipple returned. She used Efudex for 2 weeks and Poly-MVA 20 teaspoons and once again the symptoms completely subsided. JF resumed taking the Poly-MVA 8 teaspoons per day.

On March 13, 2007, JF had a follow up with her radiation oncologist. He remarked that he was surprised at how well her breast had healed from the surgery and radiation treatment. He also commented that he thought she looked great.

Around June 15, 2007 the redness around the nipple returned and JF saw and felt some blood vessels. She also lost the erectile function of her aerola. She used the Efudex again and increased the Poly-MVA to 20 teaspoons per day. The redness around the nipple and the blood vessels completely subsided. However, the lost of the erectile function of the aerola remained. She saw her physician on June 26, 2007 and he felt that her liver was enlarged. However, the ultrasound of the liver was normal. Her physician felt that it was possible that the use of Efudex irritated her gallbladder.

JF saw her radiation oncologist for her check up on July 10, 2007. The oncologist performed a physical exam and the breast and lymph nodes were normal. She explained the new problem with the aerola. The physician was able to offer an explanation. JF had traveled to Irian Jaya to scuba dive and took Malarone, an anti-malarial medication. The loss of erectile function of the aerola was most probably due to the Malarone (which has numerous serious side-effects) plus the residual effect of the electron beam booster she had received with radiation therapy. It is possible that this issue may subside. Her radiation oncologist keeps suggesting more radiation therapy despite that fact that she has no evidence of breast cancer. JF refuses further radiation treatment at this time.

JF has also added other supplements to her regimen including artemisinin and CoQ10 that were specifically added to help prevent the return of breast cancer and are synergistic with Poly-MVA. She feels great and lives a full and active life.


Case study written by Dr. Shari Lieberman as a part of the Poly-MVA Best Case Series.